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Podofilox

A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

14+ PubMed studies analyzed · 5 RCTs · Evidence Score: 42.7

Research Domains

Podofilox has been studied across 5 research domains including 🔬 Oncology, ✨ Skin & Hair, 😴 Sleep, 💊 Pain, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 50% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Podofilox, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

vinblastine
54 shared targets
Colchicine
53 shared targets
Nocodazole
51 shared targets
Demecolcine
35 shared targets
Vincristine
40 shared targets
Vorinostat
28 shared targets
Melphalan
29 shared targets
Noscapine
21 shared targets
Ciclopirox
23 shared targets
cycloheximide
30 shared targets
Loading evidence profile...

This evidence profile for Podofilox is generated deterministically from 14 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.