APOBEC3G mediated resistance to HIV-1 infection
REACTOME PATHWAYThe APOBEC3G mediated resistance to HIV-1 infection pathway (Reactome ID: R-HSA-180689) involves 2 genes and is affected by 23 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting APOBEC3G mediated resistance to HIV-1 infection
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 2 | Ampicillin Semi-synthetic derivative of penicillin that functions as | — | 294 |
| 3 | Cefixime | — | 300 |
| 4 | Levodopa | — | 297 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 6 | Methylene Blue | — | 200 |
| 7 | Biotin | — | 297 |
| 8 | Ethidium | — | 300 |
| 9 | furylfuramide | — | 82 |
| 10 | Demeclocycline | — | 5 |
| 11 | Edaravone | — | 298 |
| 12 | Methyldopa | — | 297 |
| 13 | alphitonin [Supplementary Concept] from | — | 300 |
| 14 | Anthralin | — | 299 |
| 15 | sulfameter | — | 52 |
| 16 | DEAD-box RNA Helicases | — | 169 |
| 17 | Thioctic Acid | — | 298 |
| 18 | Resveratrol | — | 298 |
| 19 | Cefotetan | — | 299 |
| 20 | Dimethylphenylpiperazinium Iodide | — | 33 |
| 21 | mg624 | — | 3 |
| 22 | streptonigrin | — | 299 |
| 23 | Thioctic Acid | — | 300 |
About the APOBEC3G mediated resistance to HIV-1 infection Pathway
The APOBEC3G mediated resistance to HIV-1 infection pathway is catalogued in Reactome (ID: R-HSA-180689) and involves 2 genes. In the BiohacksAI corpus, 23 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include APOBEC3G, PSIP1.