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Thioctic Acid

An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

300+ PubMed studies analyzed · 12 RCTs · Evidence Score: 42.5

Research Domains

Thioctic Acid has been studied across 18 research domains including 🔥 Metabolic, 🫁 Liver & Detox, 🔬 Inflammation, ✨ Skin & Hair, 🧘 Stress & Anxiety. The primary research focus is 🔥 Metabolic with 15% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Thioctic Acid, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

DEAD-box
23 shared targets
Thioctic
23 shared targets
Demeclocycline
12 shared targets
Cefotetan
8 shared targets
Rosmarinic
8 shared targets
Methyldopa
11 shared targets
Cefixime
6 shared targets
Ampicillin
5 shared targets
Picloram
4 shared targets
Levodopa
7 shared targets
Loading evidence profile...

This evidence profile for Thioctic Acid is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.