Regulation of gap junction activity
REACTOME PATHWAYThe Regulation of gap junction activity pathway (Reactome ID: R-HSA-191650) involves 1 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of gap junction activity
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Resveratrol | — | 298 |
| 3 | tyrphostin ag 1478 | — | 4 |
| 4 | Sorafenib | — | 300 |
| 5 | Quercetin | — | 300 |
| 6 | Adenosine Monophosphate Adenine nucleotide containing | — | 300 |
| 7 | Afatinib | — | 297 |
| 8 | alsterpaullone | — | 12 |
| 9 | Crizotinib | — | 298 |
| 10 | kenpaullone | — | 8 |
| 11 | monorden | — | 8 |
| 12 | Niclosamide | — | 299 |
About the Regulation of gap junction activity Pathway
The Regulation of gap junction activity pathway is catalogued in Reactome (ID: R-HSA-191650) and involves 1 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SRC.