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Afatinib

A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.

297+ PubMed studies analyzed · 29 RCTs · Evidence Score: 53.6

Research Domains

Afatinib has been studied across 10 research domains including 🔬 Oncology, 🫘 Kidney, ⏳ Longevity & Aging, 🧠 Focus & Attention, ⚡ Energy & Fatigue. The primary research focus is 🔬 Oncology with 79% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Afatinib, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

gefitinib
33 shared targets
tyrphostin
24 shared targets
erlotinib
31 shared targets
canertinib
31 shared targets
vandetanib
29 shared targets
sb
22 shared targets
Dasatinib
34 shared targets
pictilisib
22 shared targets
Vemurafenib
15 shared targets
2-Methoxyestradiol
13 shared targets
Loading evidence profile...

This evidence profile for Afatinib is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.