Neurophilin interactions with VEGF and VEGFR
REACTOME PATHWAYThe Neurophilin interactions with VEGF and VEGFR pathway (Reactome ID: R-HSA-194306) involves 3 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Neurophilin interactions with VEGF and VEGFR
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Axitinib | — | 298 |
| 3 | Crizotinib | — | 298 |
| 4 | kenpaullone | — | 8 |
| 5 | sp600125 | — | 117 |
| 6 | Quercetin | — | 300 |
| 7 | Avapritinib | — | 246 |
| 8 | Dasatinib | — | 299 |
| 9 | tyrphostin ag 1295 | — | 1 |
| 10 | Vemurafenib | — | 298 |
| 11 | Dactinomycin | — | 297 |
About the Neurophilin interactions with VEGF and VEGFR Pathway
The Neurophilin interactions with VEGF and VEGFR pathway is catalogued in Reactome (ID: R-HSA-194306) and involves 3 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FLT1, KDR, NRP2.