Calcineurin activates NFAT
REACTOME PATHWAYThe Calcineurin activates NFAT pathway (Reactome ID: R-HSA-2025928) involves 1 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Calcineurin activates NFAT
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sirolimus | — | 300 |
| 2 | cycloheximide | — | 300 |
| 3 | Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against | — | 299 |
| 4 | Everolimus | — | 297 |
About the Calcineurin activates NFAT Pathway
The Calcineurin activates NFAT pathway is catalogued in Reactome (ID: R-HSA-2025928) and involves 1 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FKBP1A.