A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Rapamycin has been studied across 22 research domains including ⏳ Longevity & Aging, 🔬 Oncology, 🛡️ Immunity, 🏋️ Muscle & Hypertrophy, 🫘 Kidney. The primary research focus is ⏳ Longevity & Aging with 37% of studies addressing this area.
The following compounds share molecular targets with Rapamycin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Rapamycin is generated deterministically from 490 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.