COPII-mediated vesicle transport
REACTOME PATHWAYThe COPII-mediated vesicle transport pathway (Reactome ID: R-HSA-204005) involves 4 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting COPII-mediated vesicle transport
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid | — | 300 |
| 2 | Glutamic Acid | — | 297 |
| 3 | Glutamic Acid | — | 300 |
| 4 | Piracetam | — | 300 |
| 5 | aniracetam | — | 110 |
| 6 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | — | 300 |
| 7 | sp600125 | — | 117 |
| 8 | alsterpaullone | — | 12 |
| 9 | pictilisib | — | 25 |
| 10 | Pemetrexed | — | 299 |
| 11 | Methotrexate | — | 289 |
| 12 | Folic Acid | — | 296 |
| 13 | apixaban [Supplementary Concept] | — | 997 |
About the COPII-mediated vesicle transport Pathway
The COPII-mediated vesicle transport pathway is catalogued in Reactome (ID: R-HSA-204005) and involves 4 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CSNK1D, F5, FOLR1, GRIA1.