Regulation of pyruvate dehydrogenase (PDH) complex
REACTOME PATHWAYThe Regulation of pyruvate dehydrogenase (PDH) complex pathway (Reactome ID: R-HSA-204174) involves 2 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of pyruvate dehydrogenase (PDH) complex
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | egcg | — | 300 |
| 2 | Rutin | — | 300 |
| 3 | Oxaprozin | — | 181 |
| 4 | Pioglitazone | — | 297 |
| 5 | streptonigrin | — | 299 |
| 6 | chrysin | — | 300 |
| 7 | fisetin | — | 78 |
About the Regulation of pyruvate dehydrogenase (PDH) complex Pathway
The Regulation of pyruvate dehydrogenase (PDH) complex pathway is catalogued in Reactome (ID: R-HSA-204174) and involves 2 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include DLD, PDK1.