p75NTR recruits signalling complexes
REACTOME PATHWAYThe p75NTR recruits signalling complexes pathway (Reactome ID: R-HSA-209543) involves 3 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting p75NTR recruits signalling complexes
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Sorafenib | — | 300 |
| 3 | Afatinib | — | 297 |
| 4 | Axitinib | — | 298 |
| 5 | alsterpaullone | — | 12 |
| 6 | Oxyphenbutazone | — | 300 |
| 7 | Anisomycin | — | 247 |
| 8 | cycloheximide | — | 300 |
| 9 | Dasatinib | — | 299 |
| 10 | Vemurafenib | — | 298 |
| 11 | Aurintricarboxylic Acid | — | 184 |
| 12 | chicoric acid | — | 117 |
| 13 | sp600125 | — | 117 |
About the p75NTR recruits signalling complexes Pathway
The p75NTR recruits signalling complexes pathway is catalogued in Reactome (ID: R-HSA-209543) and involves 3 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include IKBKB, IRAK1, RIPK2.