Basigin interactions
REACTOME PATHWAYThe Basigin interactions pathway (Reactome ID: R-HSA-210991) involves 3 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Basigin interactions
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Digoxin | — | 299 |
| 2 | Ouabain | — | 300 |
| 3 | Digitoxigenin 3 beta,14-Dihydroxy-5 beta-card-20(22)enolide. | — | 300 |
| 4 | Digitoxin | — | 300 |
| 5 | Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide. | — | 300 |
| 6 | Strophanthidin 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide. | — | 300 |
About the Basigin interactions Pathway
The Basigin interactions pathway is catalogued in Reactome (ID: R-HSA-210991) and involves 3 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ATP1B1, ATP1B2, ATP1B3.