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Ouabain

A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.

300+ PubMed studies analyzed · 1 RCTs · Evidence Score: 37.9

Research Domains

Ouabain has been studied across 22 research domains including ⚡ Energy & Fatigue, ❤️ Cardiovascular, 🫘 Kidney, 🦴 Bone & Joint, 🔬 Oncology. The primary research focus is ⚡ Energy & Fatigue with 48% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Ouabain, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Digitoxin
36 shared targets
Digoxin
40 shared targets
Deslanoside
15 shared targets
Proscillaridin
15 shared targets
Digitoxigenin
15 shared targets
Digoxigenin
15 shared targets
Emetine
19 shared targets
Tripterygium
15 shared targets
Azacitidine
18 shared targets
Azacitidine
18 shared targets
Loading evidence profile...

This evidence profile for Ouabain is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.