Sterols are 12-hydroxylated by CYP8B1
REACTOME PATHWAYThe Sterols are 12-hydroxylated by CYP8B1 pathway (Reactome ID: R-HSA-211994) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Sterols are 12-hydroxylated by CYP8B1
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Clotrimazole | — | 296 |
| 2 | Econazole | — | 299 |
| 3 | Miconazole | — | 298 |
About the Sterols are 12-hydroxylated by CYP8B1 Pathway
The Sterols are 12-hydroxylated by CYP8B1 pathway is catalogued in Reactome (ID: R-HSA-211994) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CYP8B1.