Regulation of innate immune responses to cytosolic DNA
REACTOME PATHWAYThe Regulation of innate immune responses to cytosolic DNA pathway (Reactome ID: R-HSA-3134975) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of innate immune responses to cytosolic DNA
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | amlexanox | — | 96 |
| 2 | Axitinib | — | 298 |
| 3 | Crizotinib | — | 298 |
About the Regulation of innate immune responses to cytosolic DNA Pathway
The Regulation of innate immune responses to cytosolic DNA pathway is catalogued in Reactome (ID: R-HSA-3134975) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include TBK1.