Cytosolic tRNA aminoacylation
REACTOME PATHWAYThe Cytosolic tRNA aminoacylation pathway (Reactome ID: R-HSA-379716) involves 3 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Cytosolic tRNA aminoacylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sirolimus | — | 300 |
| 2 | methyl 13-(alpha-naphthalene)aminodeisopropyldehydroabietate [Supplementary Concept] | — | 161 |
| 3 | Mupirocin | — | 299 |
About the Cytosolic tRNA aminoacylation Pathway
The Cytosolic tRNA aminoacylation pathway is catalogued in Reactome (ID: R-HSA-379716) and involves 3 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include IARS1, KARS1, LARS1.