tRNA Aminoacylation
REACTOME PATHWAYThe tRNA Aminoacylation pathway (Reactome ID: R-HSA-379724) involves 4 genes and is affected by 4 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting tRNA Aminoacylation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sirolimus | — | 300 |
| 2 | Chloramphenicol | — | 297 |
| 3 | methyl 13-(alpha-naphthalene)aminodeisopropyldehydroabietate [Supplementary Concept] | — | 161 |
| 4 | Mupirocin | — | 299 |
About the tRNA Aminoacylation Pathway
The tRNA Aminoacylation pathway is catalogued in Reactome (ID: R-HSA-379724) and involves 4 genes. In the BiohacksAI corpus, 4 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include IARS1, KARS1, LARS1, MARS2.