Free fatty acids regulate insulin secretion
REACTOME PATHWAYThe Free fatty acids regulate insulin secretion pathway (Reactome ID: R-HSA-400451) involves 3 genes and is affected by 17 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Free fatty acids regulate insulin secretion
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aripiprazole | — | 298 |
| 2 | Bisphenol A-Glycidyl Methacrylate | — | 197 |
| 3 | Calcimycin | — | 216 |
| 4 | Equilin | — | 216 |
| 5 | Fluspirilene | — | 74 |
| 6 | Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. | — | 297 |
| 7 | Sphingosine | — | 300 |
| 8 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 9 | Linoleic Acid | — | 300 |
| 10 | alpha-Linolenic Acid | — | 300 |
| 11 | Dehydroepiandrosterone Sulfate | — | 300 |
| 12 | Oleic Acid | — | 112 |
| 13 | Myristic Acid | — | 300 |
| 14 | Palmitic Acid | — | 300 |
| 15 | gamma-Linolenic Acid | — | 300 |
| 16 | Cefixime | — | 300 |
| 17 | Emtricitabine | — | 292 |
About the Free fatty acids regulate insulin secretion Pathway
The Free fatty acids regulate insulin secretion pathway is catalogued in Reactome (ID: R-HSA-400451) and involves 3 genes. In the BiohacksAI corpus, 17 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FFAR1, GNA15, PLCB3.