What compounds affect the P2Y receptors pathway?

18 compounds in the BiohacksAI corpus have documented interactions with genes in the P2Y receptors pathway (Reactome ID: R-HSA-417957). These compounds target 9 genes within this pathway.

What genes are in the P2Y receptors pathway?

The P2Y receptors pathway involves 9 genes. Key genes include: GPR17, P2RY1, P2RY11, P2RY12, P2RY13, P2RY14, P2RY2, P2RY4, P2RY6.

P2Y receptors

REACTOME PATHWAY

Reactome: R-HSA-4179579 genes18 compounds

The P2Y receptors pathway (Reactome ID: R-HSA-417957) involves 9 genes and is affected by 18 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

GPR17 P2RY1 P2RY11 P2RY12 P2RY13 P2RY14 P2RY2 P2RY4 P2RY6

Compounds Affecting P2Y receptors

#	Compound	Targets Hit	Studies
1	Adenosine Triphosphate	—	300
2	Suramin	—	300
3	Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate).	—	300
4	Uridine Triphosphate Uridine 5'-(tetrahydrogen triphosphate).	—	300
5	Uridine Diphosphate Glucose	—	300
6	Uridine Diphosphate	—	300
7	Adenosine Monophosphate Adenine nucleotide containing	—	300
8	Uridine Diphosphate Galactose	—	180
9	Leukotriene E4	—	300
10	Ticagrelor	—	299
11	NAD	—	300
12	NAD	—	300
13	NAD	—	300
14	Leukotriene C4	—	300
15	Aminolevulinic Acid	—	299
16	Guanosine Triphosphate Guanosine 5'-(tetrahydrogen triphosphate).	—	300
17	Inosine Triphosphate Inosine 5'-(tetrahydrogen triphosphate).	—	266
18	Uridine Diphosphate Glucuronic Acid	—	89

About the P2Y receptors Pathway

The P2Y receptors pathway is catalogued in Reactome (ID: R-HSA-417957) and involves 9 genes. In the BiohacksAI corpus, 18 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GPR17, P2RY1, P2RY11, P2RY12, P2RY13.