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Leukotriene C4

The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)

300+ PubMed studies analyzed · 2 RCTs · Evidence Score: 45.3

Research Domains

Leukotriene C4 has been studied across 17 research domains including 🫁 Liver & Detox, 🫁 Respiratory, 🔬 Inflammation, 🦴 Bone & Joint, ❤️ Cardiovascular. The primary research focus is 🫁 Liver & Detox with 24% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Leukotriene C4, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

pranlukast
3 shared targets
Leukotriene
3 shared targets
Leukotriene
2 shared targets
Uridine
2 shared targets
zafirlukast
2 shared targets
bufo
2 shared targets
mylabris
2 shared targets
lycopus
2 shared targets
curculigo
2 shared targets
anemarrhena
2 shared targets
Loading evidence profile...

This evidence profile for Leukotriene C4 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.