Reduction of cytosolic Ca++ levels
REACTOME PATHWAYThe Reduction of cytosolic Ca++ levels pathway (Reactome ID: R-HSA-418359) involves 3 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Reduction of cytosolic Ca++ levels
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | paxilline | — | 42 |
| 2 | Thapsigargin | — | 300 |
About the Reduction of cytosolic Ca++ levels Pathway
The Reduction of cytosolic Ca++ levels pathway is catalogued in Reactome (ID: R-HSA-418359) and involves 3 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ATP2A1, ATP2A2, ATP2A3.