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Thapsigargin

A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.

300+ PubMed studies analyzed · Evidence Score: 40.6

Research Domains

Thapsigargin has been studied across 20 research domains including 🦴 Bone & Joint, ⚡ Energy & Fatigue, 🔬 Oncology, 🧘 Stress & Anxiety, 🧠 Focus & Attention. The primary research focus is 🦴 Bone & Joint with 68% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Thapsigargin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Trabectedin
8 shared targets
Epirubicin
8 shared targets
Deslanoside
9 shared targets
Teniposide
6 shared targets
Puromycin
7 shared targets
Homoharringtonine
5 shared targets
Tripterygium
11 shared targets
monorden
7 shared targets
withaferin
8 shared targets
Emetine
13 shared targets
Loading evidence profile...

This evidence profile for Thapsigargin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.