SIRT1 negatively regulates rRNA expression
REACTOME PATHWAYThe SIRT1 negatively regulates rRNA expression pathway (Reactome ID: R-HSA-427359) involves 2 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting SIRT1 negatively regulates rRNA expression
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | s adenosylhomocysteine | — | 300 |
| 2 | Cyproheptadine | — | 299 |
| 3 | Gliotoxin | — | 300 |
| 4 | Suramin | — | 300 |
| 5 | Resveratrol | — | 298 |
About the SIRT1 negatively regulates rRNA expression Pathway
The SIRT1 negatively regulates rRNA expression pathway is catalogued in Reactome (ID: R-HSA-427359) and involves 2 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SIRT1, SUV39H1.