BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
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Cyproheptadine

A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.

299+ PubMed studies analyzed · 30 RCTs · Evidence Score: 44.9

Research Domains

Cyproheptadine has been studied across 18 research domains including 🌤️ Mood & Depression, 😴 Sleep, 🔬 Oncology, 🧬 Hormones, 🔥 Metabolic. The primary research focus is 🌤️ Mood & Depression with 35% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Cyproheptadine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Nortriptyline
49 shared targets
Mianserin
46 shared targets
Amitriptyline
47 shared targets
Promethazine
40 shared targets
Pergolide
32 shared targets
Quetiapine
36 shared targets
Amoxapine
44 shared targets
Maprotiline
37 shared targets
Metergoline
43 shared targets
Cinnarizine
30 shared targets
Loading evidence profile...

This evidence profile for Cyproheptadine is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.