KSRP (KHSRP) binds and destabilizes mRNA
REACTOME PATHWAYThe KSRP (KHSRP) binds and destabilizes mRNA pathway (Reactome ID: R-HSA-450604) involves 2 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting KSRP (KHSRP) binds and destabilizes mRNA
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Dasatinib | — | 299 |
| 3 | Afatinib | — | 297 |
| 4 | Anisomycin | — | 247 |
| 5 | isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from | — | 300 |
| 6 | withaferin | — | 300 |
| 7 | egcg | — | 300 |
| 8 | fisetin | — | 78 |
| 9 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 10 | Quercetin | — | 300 |
| 11 | Celecoxib | — | 295 |
| 12 | tyrphostin ag 1478 | — | 4 |
About the KSRP (KHSRP) binds and destabilizes mRNA Pathway
The KSRP (KHSRP) binds and destabilizes mRNA pathway is catalogued in Reactome (ID: R-HSA-450604) and involves 2 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAPK11, MAPK14.