Activation of kainate receptors upon glutamate binding
REACTOME PATHWAYThe Activation of kainate receptors upon glutamate binding pathway (Reactome ID: R-HSA-451326) involves 2 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of kainate receptors upon glutamate binding
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Glutamic Acid | — | 297 |
| 2 | Glutamic Acid | — | 300 |
| 3 | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid | — | 300 |
| 4 | Cefixime | — | 300 |
| 5 | Emtricitabine | — | 292 |
About the Activation of kainate receptors upon glutamate binding Pathway
The Activation of kainate receptors upon glutamate binding pathway is catalogued in Reactome (ID: R-HSA-451326) and involves 2 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GRIK1, PLCB3.