SUMOylation of DNA methylation proteins
REACTOME PATHWAYThe SUMOylation of DNA methylation proteins pathway (Reactome ID: R-HSA-4655427) involves 3 genes and is affected by 14 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting SUMOylation of DNA methylation proteins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | s adenosylhomocysteine | — | 300 |
| 2 | Cefdinir | — | 298 |
| 3 | Cefixime | — | 300 |
| 4 | Oxytetracycline | — | 300 |
| 5 | egcg | — | 300 |
| 6 | Oleic Acid | — | 112 |
| 7 | Anthralin | — | 299 |
| 8 | Azacitidine | — | 298 |
| 9 | Azacitidine | — | 300 |
| 10 | Carboxin | — | 174 |
| 11 | Decitabine | — | 298 |
| 12 | Fluorometholone | — | 299 |
| 13 | Uridine | — | 300 |
| 14 | Hexachlorophene | — | 300 |
About the SUMOylation of DNA methylation proteins Pathway
The SUMOylation of DNA methylation proteins pathway is catalogued in Reactome (ID: R-HSA-4655427) and involves 3 genes. In the BiohacksAI corpus, 14 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include DNMT1, DNMT3B, SUMO1.