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Decitabine

An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

298+ PubMed studies analyzed · 16 RCTs · Evidence Score: 50.5

Research Domains

Decitabine has been studied across 10 research domains including 🔬 Oncology, 😴 Sleep, 🛡️ Immunity, 🧬 Hormones, 🔬 Inflammation. The primary research focus is 🔬 Oncology with 40% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Decitabine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Thioinosine
9 shared targets
Deferasirox
10 shared targets
Itraconazole
8 shared targets
Trabectedin
7 shared targets
Polidocanol
9 shared targets
Melengestrol
8 shared targets
trequinsin
10 shared targets
deguelin
6 shared targets
Fluocinonide
6 shared targets
Proscillaridin
7 shared targets
Loading evidence profile...

This evidence profile for Decitabine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.