What compounds affect the Defective CYP1B1 causes Glaucoma pathway?

19 compounds in the BiohacksAI corpus have documented interactions with genes in the Defective CYP1B1 causes Glaucoma pathway (Reactome ID: R-HSA-5579000). These compounds target 1 genes within this pathway.

What genes are in the Defective CYP1B1 causes Glaucoma pathway?

The Defective CYP1B1 causes Glaucoma pathway involves 1 genes. Key genes include: CYP1B1.

Defective CYP1B1 causes Glaucoma

REACTOME PATHWAY

Reactome: R-HSA-55790001 genes19 compounds

The Defective CYP1B1 causes Glaucoma pathway (Reactome ID: R-HSA-5579000) involves 1 genes and is affected by 19 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CYP1B1

Compounds Affecting Defective CYP1B1 causes Glaucoma

#	Compound	Targets Hit	Studies
1	Quercetin	—	300
2	chrysin	—	300
3	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
4	Berberine	—	300
5	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
6	pterostilbene	—	299
7	Resveratrol	—	298
8	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	—	300
9	Kaempferols	—	300
10	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
11	Carvedilol	—	296
12	cbd	—	298
13	Kaempferols	—	300
14	plumbagin [Supplementary Concept]	—	300
15	cannabidiol	—	296
16	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
17	Hesperidin	—	300
18	scutellarein	—	113
19	tamarixetin	—	26

About the Defective CYP1B1 causes Glaucoma Pathway

The Defective CYP1B1 causes Glaucoma pathway is catalogued in Reactome (ID: R-HSA-5579000) and involves 1 genes. In the BiohacksAI corpus, 19 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CYP1B1.