An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Berberine has been studied across 22 research domains including 🔥 Metabolic, 🔬 Oncology, ❤️ Cardiovascular, 🔬 Inflammation, 🧬 Hormones. The primary research focus is 🔥 Metabolic with 53% of studies addressing this area.
The following compounds share molecular targets with Berberine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Berberine is generated deterministically from 467 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.