Defective UGT1A1 causes hyperbilirubinemia
REACTOME PATHWAYThe Defective UGT1A1 causes hyperbilirubinemia pathway (Reactome ID: R-HSA-5579002) involves 1 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective UGT1A1 causes hyperbilirubinemia
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Pueraria | — | 300 |
| 2 | Thyroxine | — | 994 |
| 3 | Ethinyl Estradiol | — | 300 |
| 4 | Ritonavir | — | 298 |
| 5 | scutellarein | — | 113 |
| 6 | Thyroxine | — | 300 |
| 7 | ketoconazole | — | 299 |
| 8 | licochalcone | — | 267 |
About the Defective UGT1A1 causes hyperbilirubinemia Pathway
The Defective UGT1A1 causes hyperbilirubinemia pathway is catalogued in Reactome (ID: R-HSA-5579002) and involves 1 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include UGT1A1.