Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)
REACTOME PATHWAYThe Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) pathway (Reactome ID: R-HSA-5619114) involves 1 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | 2-Chloroadenosine 2-Chloroadenosine. | — | 300 |
| 2 | Adenosine | — | 298 |
| 3 | Eszopiclone | — | 296 |
| 4 | propionylpromazine hydrochloride | — | 2 |
| 5 | Choline | — | 300 |
| 6 | Harmaline | — | 300 |
| 7 | Hexachlorophene | — | 300 |
| 8 | Ritodrine | — | 87 |
| 9 | Sertraline | — | 1,000 |
| 10 | Choline | — | 300 |
| 11 | Deoxycholic Acid | — | 300 |
| 12 | pipemidic acid | — | 299 |
| 13 | Vecuronium Bromide Monoquaternary homolog of PANCURONIUM. | — | 298 |
About the Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) Pathway
The Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) pathway is catalogued in Reactome (ID: R-HSA-5619114) and involves 1 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SLC5A7.