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Sertraline

A selective serotonin uptake inhibitor that is used in the treatment of depression.

1.0k+ PubMed studies analyzed · 629 RCTs · Evidence Score: 76.2

Research Domains

Sertraline has been studied across 15 research domains including 🌤️ Mood & Depression, 🧘 Stress & Anxiety, 😴 Sleep, 🧠 Cognitive, ❤️ Cardiovascular. The primary research focus is 🌤️ Mood & Depression with 80% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Sertraline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Astemizole
47 shared targets
Promethazine
27 shared targets
Amoxapine
31 shared targets
Cinnarizine
22 shared targets
Quetiapine
22 shared targets
Nortriptyline
29 shared targets
Amitriptyline
28 shared targets
Maprotiline
27 shared targets
Domperidone
24 shared targets
lidoflazine
22 shared targets
Loading evidence profile...

This evidence profile for Sertraline is generated deterministically from 1,000 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.