Cargo concentration in the ER
REACTOME PATHWAYThe Cargo concentration in the ER pathway (Reactome ID: R-HSA-5694530) involves 3 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Cargo concentration in the ER
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid | — | 300 |
| 2 | Glutamic Acid | — | 297 |
| 3 | Glutamic Acid | — | 300 |
| 4 | Piracetam | — | 300 |
| 5 | aniracetam | — | 110 |
| 6 | Pemetrexed | — | 299 |
| 7 | Methotrexate | — | 289 |
| 8 | Folic Acid | — | 296 |
| 9 | apixaban [Supplementary Concept] | — | 997 |
About the Cargo concentration in the ER Pathway
The Cargo concentration in the ER pathway is catalogued in Reactome (ID: R-HSA-5694530) and involves 3 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include F5, FOLR1, GRIA1.