Cholesterol biosynthesis via desmosterol (Bloch pathway)
REACTOME PATHWAYThe Cholesterol biosynthesis via desmosterol (Bloch pathway) pathway (Reactome ID: R-HSA-6807047) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Cholesterol biosynthesis via desmosterol (Bloch pathway)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Clotrimazole | — | 296 |
| 2 | Econazole | — | 299 |
| 3 | Miconazole | — | 298 |
About the Cholesterol biosynthesis via desmosterol (Bloch pathway) Pathway
The Cholesterol biosynthesis via desmosterol (Bloch pathway) pathway is catalogued in Reactome (ID: R-HSA-6807047) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CYP51A1.