Question 1

What compounds affect the Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding pathway?

Accepted Answer

27 compounds in the BiohacksAI corpus have documented interactions with genes in the Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding pathway (Reactome ID: R-HSA-6814122). These compounds target 6 genes within this pathway.

Question 2

What genes are in the Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding pathway?

Accepted Answer

The Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding pathway involves 6 genes. Key genes include: CCT2, CSNK2A1, CSNK2A2, CSNK2B, GNA15, RGS7.

#	Compound	Targets Hit	Studies
1	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
2	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
3	Quercetin	—	300
4	fisetin	—	78
5	Kaempferols	—	300
6	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
7	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
8	chrysin	—	300
9	Vanillic Acid	—	300
10	ly294002	—	11
11	Dichlororibofuranosylbenzimidazole	—	26
12	Adenylyl Imidodiphosphate 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid.	—	300
13	alsterpaullone	—	12
14	kenpaullone	—	8
15	sp600125	—	117
16	pictilisib	—	25
17	Axitinib	—	298
18	Aripiprazole	—	298
19	Bisphenol A-Glycidyl Methacrylate	—	197
20	Calcimycin	—	216
21	Equilin	—	216
22	Fluspirilene	—	74
23	Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables.	—	297
24	Sphingosine	—	300
25	Astemizole Antihistamine drug now withdrawn from	—	280
26	egcg	—	300
27	Methylene Blue	—	200

BiohacksAI

Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Genes in this Pathway

Compounds Affecting Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

About the Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Pathway