Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
REACTOME PATHWAYThe Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes pathway (Reactome ID: R-HSA-69200) involves 2 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | alsterpaullone | — | 12 |
| 2 | kenpaullone | — | 8 |
| 3 | Aurintricarboxylic Acid | — | 184 |
| 4 | Methylergonovine | — | 14 |
| 5 | sp600125 | — | 117 |
| 6 | Adenosine Triphosphate | — | 300 |
About the Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Pathway
The Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes pathway is catalogued in Reactome (ID: R-HSA-69200) and involves 2 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNE2, CDK2.