Glycogen breakdown (glycogenolysis)
REACTOME PATHWAYThe Glycogen breakdown (glycogenolysis) pathway (Reactome ID: R-HSA-70221) involves 5 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Glycogen breakdown (glycogenolysis)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | 1-Deoxynojirimycin | — | 299 |
| 2 | Quercetin | — | 300 |
| 3 | Afatinib | — | 297 |
| 4 | caffeic acid | — | 300 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 6 | Rutin | — | 300 |
| 7 | amlexanox | — | 96 |
| 8 | Carbaryl | — | 300 |
| 9 | Doxazosin | — | 24 |
| 10 | Catechin | — | 300 |
| 11 | 4-Hydroxybenzoate-3-Monooxygenase | — | 300 |
| 12 | sp600125 | — | 117 |
| 13 | alsterpaullone | — | 12 |
About the Glycogen breakdown (glycogenolysis) Pathway
The Glycogen breakdown (glycogenolysis) pathway is catalogued in Reactome (ID: R-HSA-70221) and involves 5 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AGL, GAA, PHKG1, PHKG2, PYGL.