Platelet Adhesion to exposed collagen
REACTOME PATHWAYThe Platelet Adhesion to exposed collagen pathway (Reactome ID: R-HSA-75892) involves 3 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Platelet Adhesion to exposed collagen
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Crizotinib | — | 298 |
| 3 | kenpaullone | — | 8 |
| 4 | Sorafenib | — | 300 |
| 5 | tyrphostin ag 1478 | — | 4 |
| 6 | Rosmarinic Acid | — | 300 |
| 7 | Genistein | — | 300 |
| 8 | egcg | — | 300 |
| 9 | Acetic Acid Product of | — | 300 |
| 10 | alsterpaullone | — | 12 |
| 11 | sp600125 | — | 117 |
| 12 | Losartan | — | 1,000 |
| 13 | gamma-Aminobutyric Acid | — | 300 |
About the Platelet Adhesion to exposed collagen Pathway
The Platelet Adhesion to exposed collagen pathway is catalogued in Reactome (ID: R-HSA-75892) and involves 3 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FYN, GP6, LYN.