RNA Polymerase III Transcription Initiation
REACTOME PATHWAYThe RNA Polymerase III Transcription Initiation pathway (Reactome ID: R-HSA-76046) involves 1 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RNA Polymerase III Transcription Initiation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Famotidine | — | 296 |
| 2 | Guanfacine | — | 294 |
| 3 | N-Methylscopolamine | — | 299 |
| 4 | Sumatriptan | — | 298 |
| 5 | thiamine | — | 299 |
About the RNA Polymerase III Transcription Initiation Pathway
The RNA Polymerase III Transcription Initiation pathway is catalogued in Reactome (ID: R-HSA-76046) and involves 1 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include POU2F1.