The AIM2 inflammasome
REACTOME PATHWAYThe The AIM2 inflammasome pathway (Reactome ID: R-HSA-844615) involves 1 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting The AIM2 inflammasome
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | cbd | — | 298 |
| 2 | Dehydroepiandrosterone Sulfate | — | 300 |
| 3 | cannabidiol | — | 296 |
| 4 | Disulfiram | — | 297 |
| 5 | Ethinyl Estradiol | — | 300 |
| 6 | Hexachlorophene | — | 300 |
| 7 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 8 | Norethynodrel | — | 299 |
| 9 | Thioridazine | — | 35 |
About the The AIM2 inflammasome Pathway
The The AIM2 inflammasome pathway is catalogued in Reactome (ID: R-HSA-844615) and involves 1 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CASP1.