Activation of the TFAP2 (AP-2) family of transcription factors
REACTOME PATHWAYThe Activation of the TFAP2 (AP-2) family of transcription factors pathway (Reactome ID: R-HSA-8866907) involves 2 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Activation of the TFAP2 (AP-2) family of transcription factors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Papaverine | — | 299 |
| 2 | Colchicine | — | 300 |
| 3 | Etazolate | — | 66 |
| 4 | Nocodazole Nocodazole is | — | 215 |
| 5 | plumbagin [Supplementary Concept] | — | 300 |
| 6 | egcg | — | 300 |
| 7 | 11-hydroxypalmatine [Supplementary Concept] | — | 238 |
About the Activation of the TFAP2 (AP-2) family of transcription factors Pathway
The Activation of the TFAP2 (AP-2) family of transcription factors pathway is catalogued in Reactome (ID: R-HSA-8866907) and involves 2 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CREBBP, EP300.