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BiohacksAI

Evidence-Based Biohacking

Patent Pending

TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation

REACTOME PATHWAY
Reactome: R-HSA-88694962 genes11 compounds

The TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation pathway (Reactome ID: R-HSA-8869496) involves 2 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

HSPD1NPM1

Compounds Affecting TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation

#CompoundTargets HitStudies
1Arachidonic Acid—245
2egcg—300
3plumbagin [Supplementary Concept]—300
4Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).—300
5Adapalene—296
6Aurintricarboxylic Acid—184
7Evans Blue—300
8Hexachlorophene—300
9Lithocholic Acid—300
10rafoxanide—172
11Crizotinib—298

About the TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation Pathway

The TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation pathway is catalogued in Reactome (ID: R-HSA-8869496) and involves 2 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HSPD1, NPM1.