BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Adapalene

A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.

296+ PubMed studies analyzed · 69 RCTs · Evidence Score: 55.2

Research Domains

Adapalene has been studied across 8 research domains including ✨ Skin & Hair, 🔬 Inflammation, 🫁 Liver & Detox, 🔬 Oncology, ⏳ Longevity & Aging. The primary research focus is ✨ Skin & Hair with 21% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Adapalene, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Levonorgestrel
13 shared targets
Norgestrel
13 shared targets
Methylnitronitrosoguanidine
8 shared targets
Pregnenolone
9 shared targets
Chlormadinone
11 shared targets
Spironolactone
12 shared targets
Ethynodiol
12 shared targets
Potassium
9 shared targets
o-Phthalaldehyde
11 shared targets
Proscillaridin
9 shared targets
Loading evidence profile...

This evidence profile for Adapalene is generated deterministically from 296 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.