Reuptake of GABA
REACTOME PATHWAYThe Reuptake of GABA pathway (Reactome ID: R-HSA-888593) involves 2 genes and is affected by 2 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Reuptake of GABA
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | gamma-Aminobutyric Acid | — | 300 |
| 2 | Tiagabine | — | 298 |
About the Reuptake of GABA Pathway
The Reuptake of GABA pathway is catalogued in Reactome (ID: R-HSA-888593) and involves 2 genes. In the BiohacksAI corpus, 2 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SLC6A11, SLC6A12.