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Tiagabine

A nipecotic acid derivative that acts as a GABA uptake inhibitor and anticonvulsant agent. It is used in the treatment of EPILEPSY, for refractory PARTIAL SEIZURES.

298+ PubMed studies analyzed · 38 RCTs · Evidence Score: 50.4

Research Domains

Tiagabine has been studied across 13 research domains including 🧘 Stress & Anxiety, 😴 Sleep, 🧠 Memory, 🧠 Cognitive, 🌤️ Mood & Depression. The primary research focus is 🧘 Stress & Anxiety with 49% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Tiagabine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

gamma-Aminobutyric
2 shared targets
bufo
2 shared targets
aucklandia
2 shared targets
rehmannia
2 shared targets
mentha
2 shared targets
sophora
2 shared targets
stemona
2 shared targets
tussilago
2 shared targets
verbena
2 shared targets
bupleurum
2 shared targets
Loading evidence profile...

This evidence profile for Tiagabine is generated deterministically from 298 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.