RUNX1 regulates expression of components of tight junctions
REACTOME PATHWAYThe RUNX1 regulates expression of components of tight junctions pathway (Reactome ID: R-HSA-8935964) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RUNX1 regulates expression of components of tight junctions
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aurintricarboxylic Acid | — | 184 |
| 2 | Dihydroxyphenylalanine | — | 300 |
| 3 | Disulfiram | — | 297 |
| 4 | Ethidium | — | 300 |
| 5 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 6 | Daunorubicin | — | 298 |
| 7 | Fusaric Acid | — | 300 |
| 8 | Harmaline | — | 300 |
About the RUNX1 regulates expression of components of tight junctions Pathway
The RUNX1 regulates expression of components of tight junctions pathway is catalogued in Reactome (ID: R-HSA-8935964) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CBFB, RUNX1.