RUNX3 Regulates Immune Response and Cell Migration
REACTOME PATHWAYThe RUNX3 Regulates Immune Response and Cell Migration pathway (Reactome ID: R-HSA-8949275) involves 2 genes and is affected by 24 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RUNX3 Regulates Immune Response and Cell Migration
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Inositol | — | 300 |
| 2 | Phenylbutazone | — | 300 |
| 3 | Sulfinpyrazone | — | 300 |
| 4 | Chlorogenic Acid | — | 300 |
| 5 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 6 | Prednisolone | — | 1,000 |
| 7 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 8 | Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide. | — | 300 |
| 9 | Enoximone | — | 300 |
| 10 | Isocarboxazid | — | 227 |
| 11 | Oxaprozin | — | 181 |
| 12 | Quinestrol | — | 194 |
| 13 | Ranolazine | — | 297 |
| 14 | Semustine 4-Methyl derivative of LOMUSTINE; (CCNU). | — | 97 |
| 15 | sulfameter | — | 52 |
| 16 | sulfamonomethoxine | — | 253 |
| 17 | Aurintricarboxylic Acid | — | 184 |
| 18 | Dihydroxyphenylalanine | — | 300 |
| 19 | Disulfiram | — | 297 |
| 20 | Ethidium | — | 300 |
| 21 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 22 | Daunorubicin | — | 298 |
| 23 | Fusaric Acid | — | 300 |
| 24 | Harmaline | — | 300 |
About the RUNX3 Regulates Immune Response and Cell Migration Pathway
The RUNX3 Regulates Immune Response and Cell Migration pathway is catalogued in Reactome (ID: R-HSA-8949275) and involves 2 genes. In the BiohacksAI corpus, 24 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CBFB, ITGA4.