Digestion and absorption
REACTOME PATHWAYThe Digestion and absorption pathway (Reactome ID: R-HSA-8963743) involves 9 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Digestion and absorption
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Quercetin | — | 300 |
| 2 | scutellarein | — | 113 |
| 3 | 1-Deoxynojirimycin | — | 299 |
| 4 | phlorhizin | — | 224 |
| 5 | Canagliflozin | — | 295 |
| 6 | empagliflozin | — | 996 |
| 7 | Genistein | — | 300 |
| 8 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 9 | rafoxanide | — | 172 |
| 10 | Ezetimibe | — | 296 |
| 11 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | — | 300 |
| 12 | Glucose | — | 294 |
About the Digestion and absorption Pathway
The Digestion and absorption pathway is catalogued in Reactome (ID: R-HSA-8963743) and involves 9 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AMY1A, AMY1B, AMY1C, MGAM, NPC1L1.