LDL clearance
REACTOME PATHWAYThe LDL clearance pathway (Reactome ID: R-HSA-8964038) involves 1 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting LDL clearance
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Niclosamide | — | 299 |
| 2 | Pueraria | — | 300 |
| 3 | Genistein | — | 300 |
| 4 | Resveratrol | — | 298 |
| 5 | amlexanox | — | 96 |
| 6 | kenpaullone | — | 8 |
| 7 | pd98059 | — | 7 |
| 8 | Riluzole | — | 298 |
| 9 | tyrphostin ag 1295 | — | 1 |
About the LDL clearance Pathway
The LDL clearance pathway is catalogued in Reactome (ID: R-HSA-8964038) and involves 1 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NPC1.